Figure 1.

Cross section from seminiferous tubules of (A) control-sham, (B) 0.2 mg/kg nicotine-received and (C) 0.4 mg/kg nicotine-received groups. See intact seminiferous tubules in control group with normal spermatogenesis (NS) and no edema in interstitial connective tissue. Note seminiferous tubule with negative TDI (N.TDI), germinal epithelium dissociation (GED) in cross section from 0.2 mg/kg nicotine-received group, which is developed to complete tubular depletion (TD) and spermatogenesis arrest (SA) in 0.4 mg/kg nicotine-received animals. H&E staining, Scale bars for first row: 120 µm and scale bars for sec row: 50 µm