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. 2017 Mar 7;7:43310. doi: 10.1038/srep43310

Figure 5. Impaired IL-1β expression in IMQ-induced psoriasis-like mice by blocking CCN1 function.

Figure 5

(a) Ear thickness of IMQ-induced psoriasis-like mice (n = 6). (b) The histopathology of the skin tissue sections of the IMQ-treated mice using H&E staining. Original magnification, 200. Bar, 50 μm. CCN1 mRNA expression (c) and IL-1β mRNA expression (d) in the back skin of IMQ-induced psoriasis-like mice (n = 6). For (a,c,d), black bar, 1 mg/ml of 093G9; open bar, 1 mg/ml of control antibody (Con-IgG1). *P < 0.05, ***P < 0.001. The data represent one of three independent experiments.