Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Analogue ISV dose response and ranking based on efficacy, potency, and toxicity
| Compound | IUPAC name | Efficacy score | Potency score | Toxicity score | Total score | Rank |
|---|---|---|---|---|---|---|
| Q8 | (E)-2-(2-Quinolin-2-yl-vinyl)-benzene-1,4-diol HCl salt | 4 | 5 | 4 | 13 | 1a |
| Q18 | (Z)-2-(2-(Quinolin-2-yl)vinyl)phenol HCl salt | 4 | 4 | 4 | 12 | 2 |
| Q22 | 2-Quinolin-2-yl-ylethynylphenol HCl salt | 4 | 3 | 4 | 11 | 3 |
| Q1 | 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol | 3 | 3 | 4 | 10 | 4 |
a Highest ranking compound in ISV assay based on efficacy and potency scoring system.
