FIGURE 4.
Adipose tissue in adipoSPTko mice. A and C, fat mass and lean mass weight as a percentage of total body weight, measured by EchoMRI, in 1- and 4-month-old Sptlc1fl/fl control and adipoSPTko mice. B and D, weight of excised gonadal adipose tissue, inguinal adipose tissue, interscapular BAT, and liver in 1- and 4-month-old control and adipoSPTko mice. Data represent means ± S.E. Student's t test, 1-month-old (A): n = 13 control and n = 9 adipoSPTko; 1-month-old (B): n = 9 each genotype; 4-month-old (C and D): n = 7 control and n = 5 adipoSPTko; *, p < 0.05; **, p < 0.01; ***, p < 0.001. E, photographs of gonadal adipose tissue (top) and interscapular BAT (bottom) before excision from 4-month-old mice. F, photographs of gonadal adipose tissue (top) and interscapular BAT (bottom) after excision from 4-month-old mice. G, average daily food intake. 4-Week-old mice: n = 4 control and n = 5 adipoSPTko; 4-month-old mice: n = 5 control and n = 4 adipoSPTko.