Figure 3.

Gene expression analysis reveals the network dynamics during iMT. (A) A PCA projection plot showing microarray analysis of time course 6TCF and SGCF treatments. (B) A clustering heatmap showing differentially expressed genes during the time course experiment of 6TCF and SGCF treatments. (C) A gene expression correlation heatmap from the microarray data reveals multiple modules associated with iMT process. (D) A heatmap showing gene expression pattern of defined modules. (E) Gene expression dynamic for key regulators during the iMT process. Note that there is no significant upregulation of Pou5f1, Nanog, Esrrb or Sall4 during the iMT process.