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. 2017 Mar 7;7:43673. doi: 10.1038/srep43673

Figure 3. ceRNA competition can stabilize highly expressed proteins.

Figure 3

(A) Coefficient of variation of pT as a function of the mean protein level for a post-transcriptionally unregulated protein (black line, Inline graphic and Inline graphic), a miRNA-regulated protein (red line, Inline graphic and Inline graphic) and a ceRNA-regulated protein (blue line, Inline graphic and Inline graphic). (B) Capacity of the target’s expression channel as a function of the miRNA-competitor interaction strength. Color code same as in panel A. (C) Derepression size ΔC of the competitor as a function of the miRNA-competitor interaction strength in the case of ceRNA regulation (same parameters as panel B).