FIG. 3.
(A) SDHD mRNA expression in the indicated tissues. Total RNA was hybridized with an SDHD cDNA-containing probe. The Ppia gene, encoding cyclophilin, was used as loading control. (B) Mitochondrial succinate-dehydrogenase (MCII) and NADH-dehydrogenase (MCI) activities in mouse tissues. Data are the averages from four animals per tissue and genotype. Error bars indicate the standard error. In all tissues MCII activities in SDHD+/+ and SDHD+/− mice were significantly different (P < 0.05). Numbers in parentheses indicate the relative activity (in percent) in SDHD+/− with respect to SDHD+/+ mice.