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. 2017 Mar 5;130(5):566–573. doi: 10.4103/0366-6999.200550

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Copyright: © 2017 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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The layout of the miRNA-mRNA regulatory network. The network consists of 54 regulations (a) between downregulated miRNAs to upregulated mRNAs and 122 regulations (b) between upregulated miRNAs to downregulated mRNAs. A diamond marks miRNA and a rectangle marks the mRNA. An edge represents a regulation from miRNA to one of its targets. The miRNAs and mRNAs are colored based on their dysregulation pattern. If the miRNAs (or mRNAs) are upregulated in the RIF group, the nodes are marked by gray, otherwise they are marked by white. miRNA: MicroRNA; RIF: Repeated implantation failure.