Figure 2.

The pathological feature of Chinese patient with Muckle -Wells syndrome. The skin biopsy (H and E staining) was taken from a papule of the extension part of the forearm. (a) Slightly hyperkeratosis and slightly acanthosis of the epidermis; infiltration of lymphocytes around vessels, and scattered eosinophils in the upper dermis (×40); (b and c) abundant lymphocytes and eosinophils in the deep dermis and the subcutaneous tissue, respectively. Lymphocytes and eosinophils gradually increased from the upper dermis to the subcutaneous tissue (b: ×100, c: ×200).