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. 2017 Mar 7;9:23. doi: 10.1186/s13073-017-0414-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Miami plot of uric acid. The top panel shows the GWAS results using all SNPs imputed to the HRC reference panel, while the bottom panel shows only directly genotyped SNPs. In the Miami plot − log10 (p value) is plotted on the y-axis and chromosomal location is plotted on the x-axis. The genome-wide significance threshold after correction for multiple testing (p value < 5 × 10^–8) is indicated by a dark grey dashed line, while suggestive significance (p value < 10^–5) is indicated by a light grey dashed line