Table 5.
Relation between demographic, clinical, and biochemical findings and CMV and/or EBV as detected in serum by qualitative PCR assay in leukemic patients
| CMV orEBV alone n = 19 |
Both positive n = 9 |
Both negative n = 22 |
p value | |
|---|---|---|---|---|
| Age | 0.61 | |||
| ≤6 years (n = 23) | 7 (30.4%) | 5 (21.7%) | 11 (47.8%) | |
| >6 years (n = 27) | 12 (44.4%) | 4 (14.8%) | 11 (40.7%) | |
| Sex | 0.53 | |||
| Male (n = 26) | 11 (42.3%) | 3 (11.5%) | 12 (46.2%) | |
| Female (n = 24) | 8 (33.3%) | 6 (25%) | 10 (41.7%) | |
| Mucositis | 0.07 | |||
| Yes (n = 22) | 7 (31.8%) | 7 (31.8%) | 8 (36.4%) | |
| No (n = 28) | 12 (42.9%) | 2 (7.1%) | 14 (50.0%) | |
| Organomegaly | 0.72 | |||
| Yes (n = 35) | 14 (40.0%) | 7 (20.0%) | 14 (40.0%) | |
| No (n = 15) | 5 (33.3%) | 2 (13.3%) | 8 (53.4%) | |
| DFN (days) | 0.75 | |||
| <26.5 (n = 25) | 8 (32%) | 5 (20%) | 12 (48%) | |
| >26.5 (n = 25) | 11 (44%) | 4 (16%) | 10 (40%) | |
| ANC (×109/L) | 0.07 | |||
| <0.13 (n = 25) | 13 (52%) | 2 (8%) | 10 (40%) | |
| ≥0.13 (n = 25) | 6 (24%) | 7 (28%) | 12 (48%) | |
| Plt count (×109/L) | 0.27 | |||
| <39.5 (n = 25) | 7 (28%) | 4 (16%) | 14 (56%) | |
| ≥39.5 (n = 25) | 12 (48%) | 5 (20%) | 8 (32%) | |
| Hb (gm/dL) | 0.65 | |||
| <7.4 (n = 25) | 10 (40%) | 3 (12%) | 12 (48%) | |
| ≥7.4 (n = 25) | 9 (36%) | 6 (24%) | 10 (40%) | |
| AMC(×109/L) | 0.43 | |||
| <0.11 (n = 25) | 9 (36%) | 3 (12%) | 13 (52%) | |
| ≥0.11 (n = 25) | 10 (40%) | 6 (24%) | 9 (36%) | |
| TLC(cell/mm3) | 0.57 | |||
| <11950 (n = 25) | 11 (44%) | 5 (20%) | 9 (36%) | |
| ≥11950 (n = 25) | 8 (32%) | 4 (16%) | 13 (52%) | |
| ALC(×109/L) | 0.93 | |||
| <1.2 (n = 24) | 10 (41.7%) | 4 (16.7%) | 10 (41.7%) | |
| ≥1.2 (n = 26) | 9 (34.6%) | 5 (19.2%) | 12 (46.2%) |
Numerical factors were divided according to their median values
DFN Duration of febrile neutropenia, HG hemoglobin, TLC Total leukocytic count, Plt platelets, ANC Absolute neutrophilic count, AMC Absolute monocytic count, ALC Absolute lymphocytic count