Table 6.
Relation between demographic, clinical, and biochemical findings and CMV and/or EBV as detected in leukocytes by qualitative PCR assay in leukemic patients
| EBV alone n = 14 |
CMV alone n = 10 |
Both positive n = 9 |
Both negative n = 17 |
p value | |
|---|---|---|---|---|---|
| Age | 0.45 | ||||
| ≤6 years (n = 23) | 8 (34.8%) | 6 (26.1%) | 3 (13%) | 6 (26.1%) | |
| >6 years (n = 27) | 6 (22.2%) | 4 (14.8%) | 6 (22.2%) | 11 (40.7%) | |
| Sex | 0.94 | ||||
| Male (n = 26) | 7 (26.9%) | 6 (23.1%) | 5 (19.2%) | 8 (30.8%) | |
| Female (n = 24) | 7 (29.2%) | 4 (16.7%) | 4 (16.7%) | 9 (37.5%) | |
| Mucositis | 0.60 | ||||
| Yes (n = 22) | 4 (18.2%) | 5 (22.7%) | 5 (22.7%) | 8 (36.4%) | |
| No (n = 28) | 10 (35.7%) | 5 (17.9%) | 4 (14.3%) | 9 (32.1%) | |
| Organomegaly | 0.61 | ||||
| Yes (n = 35) | 11 (31.4%) | 8 (22.9%) | 6 (17.1%) | 10 (28.6%) | |
| No (n = 15) | 3 (20.0%)) | 2 (13.3%) | 3 (20.0%) | 7 (46.7%) | |
| DFN (days) | 0.79 | ||||
| <26.5 (n = 25) | 7 (28.0%) | 4 (16.0%) | 4 (16.0%) | 10 (40.0%) | |
| >26.5 (n = 25) | 7 (28.0%) | 6 (24.0%) | 5 (20.0%) | 7 (28.0%) | |
| ANC(×109/L) | 0.84 | ||||
| <0.13 (n = 25) | 8 (32%) | 4 (16%) | 5 (20%) | 8 (32%) | |
| ≥0.13 (n = 25) | 6 (24%) | 6 (24%) | 4 (16%) | 9 (36%) | |
| Plt count(×109/L) | 0.90 | ||||
| <39.5 (n = 25) | 7 (28.0%) | 6 (24.0%) | 4 (16.0%) | 8 (32.0%) | |
| ≥39.5 (n = 25) | 7 (28.0%) | 4 (16.0%) | 5 (20.0%) | 9 (36.0%) | |
| Hb(gm/dL) | 0.12 | ||||
| <7.4 (n = 25) | 8 (32%) | 5 (20%) | 7 (28%) | 5 (20%) | |
| ≥7.4 (n = 25) | 6 (24.0%) | 5 (20.0%) | 2 (8.0%) | 12 (48.0%) | |
| AMC(×109/L) | 0.67 | ||||
| <0.11 (n = 25) | 8 (32%) | 6 (24%) | 3 (12%) | 8 (32%) | |
| ≥0.11 (n = 25) | 6 (24%) | 4 (16%) | 6 (24%) | 9 (36%) | |
| TLC(cell/mm3) | 0.59 | ||||
| <11950 (n = 25) | 6 (24%) | 6 (24%) | 6 (24%) | 7 (28%) | |
| ≥11950 (n = 25) | 8 (32%) | 4 (16%) | 3 (12%) | 10 (40%) | |
| ALC(×109/L) | 0.79 | ||||
| <1.2 (n = 24) | 8 (33.3%) | 4 (16.7%) | 5 (20.8%) | 7 (29.2%) | |
| ≥1.2 (n = 26) | 6 (23.1%) | 6 (23.1%) | 4 (15.4%) | 10 (38.5%) |
DFN Duration of febrile neutropenia, HG hemoglobin, TLC Total leukocytic count, Plt platelets, ANC Absolute neutrophilic count, AMC Absolute monocytic count, ALC Absolute lymphocytic count