Fig. 7.

The ectopic expression of SMAD2 and ZEB1 counteracts the inhibition of migration, invasion and EMT progression induced by miR-484. a, b Transwell migration/invasion assays and three-dimensional Matrigel culture to test the cells’ abilities to migration (a) and invasion (b). c Protein levels of EMT-associated markers were assessed by western blotting after transfection for 48 h. *p < 0.05, **p < 0.01, ***p < 0.001. All the bars indicate the means ± SDs. All experiments were repeated at least three times