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. 2017 Mar 6;17:25. doi: 10.1186/s12896-017-0345-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — OD₄₅₀ values of ELISA tests for H. pylori-specific serum IgG and intestinal SIgA levels. The Lpp20 group and Lpp20 + LTB group were vaccinated with L. lactis NZ3900/pNZ8149-SP-lpp20 and the mixture of NZ3900/pNZ8149-SP-lpp20 and NZ3900/pNZ8149-SP-ltB, respectively, while the PBS group, as the control, was treated with PBS. One week after oral immunization, blood sampling was performed for half number of the mice of all the groups. The serum (1:10 diluted) and fecal samples were tested for H. pylori-specific antibodies by ELISA. Bars, mean OD₄₅₀ value; error bars, standard deviation; ^∆ the value was significantly higher than that for the PBS group (P < 0.05); * the value was significantly different from those for the other two groups (P < 0.05)