Table 1.
Patients’ characteristics at baseline
| Variables | Categories | Total n (%) |
|---|---|---|
| Total | 8230 | |
| Gender | Male | 6013 (73.1) |
| Age at baseline (years) | 18–24 | 610 (7.4) |
| 25–34 | 2681 (32.6) | |
| 35–44 | 3054 (37.1) | |
| 45–54 | 1337 (16.3) | |
| ≥55 | 548 (6.7) | |
| Mean (SD) | 38.4 (10.1) | |
| Country of origin | Italy | 6539 (80.7) |
| Others | 1561 (19.3) | |
| Year of enrolment | 2000–2002 | 2077 (25.2) |
| 2003–2006 | 2544 (30.9) | |
| 2007–2009 | 1943 (23.6) | |
| 2010–2012 | 1666 (20.2) | |
| IDU | Yes | 4516 (35.8) |
| HBV/HCV co-infection | Yes | 2430 (29.5) |
| CD4 cell count | 0–49 | 523 (6.8) |
| 50–99 | 516 (6.7) | |
| 100–199 | 1007 (13.0) | |
| 200–349 | 1733 (22.4) | |
| 350–499 | 1659 (21.5) | |
| ≥500 | 2296 (29.7) | |
| Mean (SD) | 395.5 (277.6) | |
| CD4/CD8 ratio | <0.3 | 2733 (40.3) |
| 0.3–0.45 | 1356 (20.0) | |
| ≥0.45 | 2689 (39.7) | |
| Mean (SD) | 0.4 (0.3) | |
| HIV-RNA log10 | Mean (SD) | 4.6 (1.0) |
| Late presentation | Yes | 4516 (58.6) |
| Advanced late presentation | Yes | 3135 (40.7) |
| Lymphocytes | Mean (SD) | 1962.4 (896.5) |
| Platelets | Mean (SD) | 220351.6 (80150.0) |
| Neutrophils | Mean (SD) | 2910.9 (1456.2) |
| PLR | <100 | 2675 (39.1) |
| 100–200 | 3132 (45.7) | |
| ≥200 | 1043 (15.2) | |
| Mean (SD) | 139.1 (100.8) | |
| NLR | <2 | 3826 (71.8) |
| 2.4 | 1200 (22.5) | |
| ≥4 | 305 (5.7) | |
| Mean (SD) | 1.8 (1.5) |
Late presentation refers to persons diagnosed with HIV with a CD4 cell count below 350/mm3 or with an AIDS defining event regardless of the CD4 cell count in the 6 months following HIV diagnosis. Late presentation with HIV advanced disease refers to persons diagnosed with HIV with a CD4 cell count below 200/mm3 or with an AIDS defining event, regardless of CD4 cell count in the 6 months following HIV
Abbreviations: SD standard deviation, IDU intravenous drug use, HBV Hepatitis B viruses, HCV Hepatitis C viruses, PLR platelet to lymphocyte ratio, NLR neutrophil to lymphocyte ratio