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. 2017 Mar 7;36:27. doi: 10.1186/s40880-017-0196-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Study flow chart for comparison of weekly PE and tri-weekly FEC regimens in treating locally advanced breast cancer. FEC tri-weekly 5-fluorouracil–epirubicin–cyclophosphamide regimen, PE weekly paclitaxel–epirubicin regimen, NACT neoadjuvant chemotherapy. ^#All participants who switched chemotherapy regimens had undergone surgery except one in the PE arm that was lost to follow-up