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. 2017 Mar 7;18:29. doi: 10.1186/s12868-017-0345-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Effects of time-dependent MS-DBS on adult hippocampal neurogenesis. a Representative immunofluorescence images reveal the effects of time-dependent MS-DBS on neurogenesis and differentiation. Hippocampal dentate gyrus (DG) sections stained for Sox2 (red), DCX (green), and DAPI (blue) are shown. The number of Sox2- (b) and DCX-immunopositive cells (c) was significantly lower in the lesion and probe-stimulation groups than in the normal group. However, the numbers of Sox2- and DCX-immunopositive cells were elevated in the pre- and training-stimulation groups (values represent the mean ± SEM, p < 0.05)