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. 2017 Mar 6;17:35. doi: 10.1186/s12935-017-0405-y

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Microarray analysis of gene and LncRNA expression profiles in LEE011-treated HL-60 cells. The Arraystar Human LncRNA 8 × 60 k v3.0 1 microarray was used to identify mRNA and lncRNA expression profiles in LEE011-treated HL-60 cells compared with controls. a Hierarchical clustering analysis of the 116 and 155 significantly up- and downregulated mRNAs (≥fivefold) in LEE011-treated HL-60 cells. b Hierarchical clustering analysis of the differently expressed lncRNAs with a fold-change ≥5 in LEE011-treated HL-60 cells. c Scatter-plot showing mRNA expression variation between the control group and LEE011 treated HL-60 cells. The green lines are fold-change lines (the default fold-change value given is 2.0). d Scatter-plot showing lncRNA expression variation between the control group and LEE011-treated HL-60 cells