. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: Curr Opin HIV AIDS. 2017 Jan;12(1):77–83. doi: 10.1097/COH.0000000000000331

Table 1.

Literature review 2011–2016: cancer incidence in HIV-infected children in the era of on Combination Antiretroviral Therapy

Study	Countries	Calendar years	Children included	Total follow-up time [years]	Cancer cases identified	Incidence rate per 100,000 person-years
Simard et al 2012, AIDS Cancer Match Study [10]	USA	1996 – 2007	1,370	17,734	37^*	Overall: 213 KS: 17 NHL: 132 NADC: 63
Chen et al 2015, NHIRD [11]	Taiwan	1998–2009	230	NR	7	Overall: NR KS: 150 NHL: 75 NADC: NR
Bohlius et al 2016, IeDEA-SA [9]	South Africa	2005 – 2011	11,707	29,348	Total 71, prevalent 47, incident 24^**	Overall: 82 KS: 34 NHL: 31 NADC: 17

Cancer incidence rate estimates in HIV-infected children published in the last five years.

included children and adolescents diagnosed with AIDS only;

^**

prevalent defined as: before cohort enrolment, incident: after cohort enrolment. NHIRD National Health Insurance Research Database; IeDEA-SA International Epidemiological Databases to Evaluate AIDS in Southern Africa; NR not reported.