Table 2.

Examples of studies reporting antifungal nanoparticles with in vivo and/or in vitro activity.

Antifungal agent	Type Of nanoparticle	Administration	In vivo	In vitro	References
Amphotericin B	Lipid nanoparticles	Inhalation	N/A	Candida albicans, Cryptococcus neoformans	Gangadhar et al., 2014
		Intravenous	Aspergillus fumigatus	Candida albicans, Aspergillus fumigatus	Jung et al., 2009
		Intravenous	Aspergillus fumigatus	N/A	Sheikh et al., 2010
		Intravenous	Candida albicans	N/A	Burgess et al., 2013
	Liposomes	N/A	N/A	Candida albicans, Candida tropicalis	Albasarah et al., 2010
	Magnetic nanoparticles	Nasal instilation	Paracoccidioides brasiliensis	N/A	Saldanha et al., 2016
	Nanoemulsion	Topical	N/A	Aspergillus fumigatus, Aspergilus niger, Candida albicans	Hussain et al., 2016
	Nanosuspension	Ocular	N/A	Fusarium solani	Das and Suresh, 2011
	Polymeric nanoparticles	Inhalation	Aspergillus fumigatus	N/A	Shirkhani et al., 2015
		Intraperitoneal	Aspergillus fumigatus	N/A	Van de Ven et al., 2012
		Intraperitoneal	Paracoccidioides brasiliensis	N/A	Amaral et al., 2009; Souza et al., 2015
		Intravenous	Candida albicans	N/A	Tang et al., 2014, 2015a
		Intravenous	Candida glabrata	N/A	Tang et al., 2015b
		Intravenous	Cryptococcus neoformans	N/A	Xu et al., 2011
		Intravenous	N/A	Candida albicans	Han et al., 2007
		Intravenous		Candida albicans	Zia et al., 2015
		N/A	Candida glabrata	N/A	Tang et al., 2015c
		N/A	N/A	Candida albicans	Tiyaboonchai et al., 2001; Tang et al., 2014
		N/A	N/A	Candida albicans, Candida tropicalis	Casa et al., 2015
		Ocular	N/A	Candida albicans	Zhou et al., 2013
		Ocular	N/A	Candida albicans, Aspergillus fumigatus	Zhou et al., 2013
		Oral	Candida albicans, Aspergillus fumigatus	N/A	Serrano et al., 2015
	Polymeric nanoparticles	Oral/intravenous	Aspergillus fumigatus	N/A	Italia et al., 2011
		Topical	Candida albicans, Candida glabrata, Candida parapsilosis	N/A	Sanchez et al., 2014
	Solid Lipid Nanoparticles	N/A	N/A	Candida albicans	Vieira and Carmona-Ribeiro, 2008
		Oral	N/A	Candida albicans	Chaudhari et al., 2016
Amphotericin B and Nystatin	Magnetic nanoparticles	N/A	N/A	Candida albicans	Niemirowicz et al., 2016
Fluconazole	Polymeric nanoparticles	Ocular	Candida albicans	N/A	Rençber et al., 2016
	Solid Lipid Nanoparticles	N/A	N/A	Candida albicans, Candida glabrata, Candida parapsilosis	Moazeni et al., 2016
		Topical	Candida albicans	N/A	Gupta and Vyas, 2012
Itraconazole	Lipid nanoparticles	Inhalation	Aspergillus fumigatus	N/A	Pardeike et al., 2016
	Polymeric nanoparticles	N/A	Candida albicans	N/A	Qiu et al., 2015
		N/A	N/A	Aspergillus flavus	Patel et al., 2011
		N/A	N/A	Candida albicans, Aspergillus fumigatus	Essa et al., 2012
		N/A	N/A	Paracoccidioides brasiliensis	Cunha-Azevedo et al., 2011
		N/A	N/A	Aspergillus flavus	Patel et al., 2010
	Solid Lipid Nanoparticles	Ocular	N/A	Aspergillus flavus	Mohanty et al., 2015
Miconazole	Liposomes	Topical	Candida albicans	N/A	Pandit et al., 2014
	Solid Lipid Nanoparticles	Topical	Candida albicans	N/A	Jain et al., 2010
Nystatin	Polymeric nanoparticles	N/A	N/A	Candida albicans	Mohammadi et al., 2017
Voriconazole	Polymeric nanoparticles	Oral	Candida albicans	N/A	Peng et al., 2008