Table 2. Top-ranked RNA editing SNP-EOC risk associations among all histologies (N = 10,891) or serous histology (N = 6,500) versus controls (N = 21,693), sorted by gene and p-value.

Gene	SNP	Alleles	MAF	Imputation accuracy R2	All histologies OR (95% CI)	P	FDR	Serous OR (95% CI)	P	FDR
ADAR	rs9426826	C>G	0.481	0.86	1.05 (1.02-1.09)	0.0038	0.76	1.04 (1-1.08)	0.0759	0.9996
	rs3738030	A>C	0.116	0.79	0.93 (0.89-0.98)	0.0080	0.83	0.91 (0.86-0.97)	0.0038	0.9996
ADAR3	rs77027562a	A>G	0.009	0.41	1.39 (1.17-1.64)	0.0001	0.34	1.33 (1.08-1.62)	0.0061	0.9996
	rs11250601	C>T	0.070	0.62	0.89 (0.83-0.95)	0.0007	0.34	0.9 (0.83-0.97)	0.0071	0.9996
	rs142123280b	A>G	0.001	0.48	2.08 (1.36-3.17)	0.0007	0.34	2.01 (1.23-3.29)	0.0056	0.9996
	rs4880912	T>C	0.200	0.82	1.07 (1.03-1.11)	0.0015	0.51	1.06 (1.01-1.11)	0.0267	0.9996
	rs11598359	C>T	0.005	0.45	0.68 (0.54-0.87)	0.0018	0.53	0.63 (0.47-0.86)	0.0032	0.9996
	rs6560760	C>T	0.025	0.59	1.17 (1.06-1.3)	0.0024	0.65	1.07 (0.95-1.22)	0.2688	0.9996
	rs2676202c	C>T	0.122	0.66	0.93 (0.88-0.98)	0.0038	0.76	0.9 (0.85-0.96)	0.0014	0.9996
	rs139646191	TAGAA>T	0.062	0.66	1.11 (1.03-1.18)	0.0038	0.76	1.07 (0.98-1.16)	0.1242	0.9996
	rs139812582	G>A	0.002	0.47	1.71 (1.15-2.54)	0.0078	0.83	2.03 (1.31-3.14)	0.0017	0.9996
	chr10:1419524	T>TGG	0.009	0.60	0.79 (0.65-0.95)	0.0106	0.83	0.68 (0.54-0.86)	0.0014	0.9996
	rs185147330	C>T	0.005	0.45	1.32 (1.05-1.67)	0.0176	0.86	1.54 (1.19-2)	0.0011	0.9996
SND1	rs185455523	T>A	0.008	0.56	0.68 (0.56-0.83)	0.0002	0.34	0.6 (0.46-0.77)	0.0001	0.45
	rs145106202d	G>C	0.009	0.87	0.73 (0.61-0.88)	0.0008	0.35	0.67 (0.53-0.84)	0.0006	0.9996
	rs181460088	C>T	0.008	0.80	0.73 (0.6-0.89)	0.0021	0.58	0.67 (0.52-0.86)	0.0020	0.9996
	rs199750392	G>GT	0.036	0.61	1.14 (1.05-1.25)	0.0028	0.71	1.11 (1-1.23)	0.0550	0.9996
	rs79138382	C>T	0.007	0.72	1.32 (1.09-1.61)	0.0056	0.83	1.42 (1.13-1.77)	0.0025	0.9996

Significant SNPs (P < 4.0×10⁻³) are listed and SNPs in LD (r²>0.60) with more significant SNP are not reported:

^a)7 SNPs in LD not reported

^b)12 SNPs in LD not reported

^c)1 SNP in LD not reported

^d)1 SNP in LD not reported