Table 2. Genotyping results in GDM cases and controls.
SNP | Base changa | MAFb | Reported MAFc | P value | ||
---|---|---|---|---|---|---|
Dominant model | Recessive model | Additive model | ||||
rs17584499 | C>T | 0.090 | 0.087 | 0.331 | 0.076 | 0.190 |
rs649891 | C>T | 0.217 | 0.223 | 0.418 | 0.555 | 0.654 |
rs10511544 | A>C | 0.267 | 0.267 | 0.116 | 0.003 | 0.015 |
rs10756026 | T>A | 0.253 | 0.262 | 0.041 | 0.003 | 0.005 |
rs10809070 | C>G | 0.180 | 0.175 | 0.047 | < 0.001 | 0.004 |
rs12345848 | G>A | 0.177 | 0.180 | 0.546 | 0.134 | 0.318 |
rs1323500 | T>G | 0.434 | 0.437 | 0.370 | 0.218 | 0.200 |
rs628731 | A>G | 0.250 | 0.257 | 0.243 | 0.013 | 0.058 |
Notes: Major > minor allele;
MAF in 1021 controls;
Reported MAF in Han Chinese from 1,000 genomes. Abbreviations: GDM, gestational diabetes mellitus; SNP, single nucleotide polymorphism; MAF, minor allele frequency.