Table 1.
Baseline characteristics for all subjects
| Variable | Statistic |
|---|---|
| Mean (SD) | |
| Age (years) | 61.0 (10.3) |
| Gender | N (%) |
| Male | 36 (65.5) |
| Female | 19 (34.6) |
|
Maximal Kellgren-Lawerence score in either patellofemoral or tibiofemoral compartment |
N (%) |
| 2 | 19 (37.3) |
| 3 | 29 (56.9) |
| 4 | 3 (5.9) |
| Pain | Mean (SD) |
| KOOS pain* | 46.6 (15.6) |
| Nominated activity VAS* | 7.0 (1.8) |
| MRI Volumetric Assessment | Median (IQR) |
| Synovial tissue volume (mm3) | 9667 (6320–13231) |
| Whole knee semi-quantitative assessment | |
| Synovitis† | 15 (12–16) |
| Bone marrow lesion‡ | 6 (3–9) |
| Cartilage‡ | 11.5 (6–18) |
| Osteophytes ‡ | 36 (20–53) |
*
KOOS scored from 100 (no pain) to 0 (extreme pain), Nominated activity VAS scored from 0 (no pain) - 10 (extreme pain). Abbreviations: KOOS - Knee Injury and Osteoarthritis Outcome score,
†
Sum of 7 regions (each scored 0–3)
‡
Assessed using the Whole Organ Magnetic Imaging Score. Whole knee scores calculated as the sum of individual compartment scores