Skip to main content
. 2016 Oct 15;7(47):77457–77467. doi: 10.18632/oncotarget.12681

Figure 1. Lon is over-expressed in human malignant gliomas.

Figure 1

Data mining of previously published microarrays for Lon expression was performed using the: A. Oncomine database assessing Lon Expression in Astrocytic Tumors vs. Normal Brain. All studies identified showed significant differences between the normal brain and WHO grade II, III and IV astrocytic tumors. B. Rembrandt database examining Lon expression in human GBM patients correlated to survival. Kaplan-Meier Survival plot depicting survival of all GBM patients (n=178 patients) with Lon high expression (red line), and low expression (blue line). C. Immunohistochemical staining for LONP1 in human normal brains, Grade II and GBM surgical biopsies.