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. 2016 Oct 14;7(47):77365–77377. doi: 10.18632/oncotarget.12670

Figure 6. FOXM1 inhibition effects Homologous recombination (HR) DNA repair.

Figure 6

To assay homologous recombination (HR), U251 DR-GFP cells were transfected with pCBAScel vector 24 hours prior to indicated treatments. GFP+ve cells representing HR repair events were determined by flow cytometry A. represents two-dimensional plot of GFP-specific fluorescence –FL1 (on Y axis versus light scatter (x-axis) to identify GFP+ve cells, B. represent bar graph of percentage GFP+ve cells. Two different concentrations of BO2 (RAD51 inhibitor) were used as a positive control. Data presented are the mean ± SD from at least three independent experiments. Student's t test was performed and the level of significance *indicate p < 0.05, **p < 0.005.