Skip to main content
. 2016 Oct 20;7(47):77052–77070. doi: 10.18632/oncotarget.12784

Table 1. Association of FILIP1L, Beta-catenin, and SLUG expression with clinicopathological characteristics in normal and neoplastic ovarian tissue samples.

No FILIP1L Beta–catenin SLUG
Median [IQR] p value Median [IQR p value Median [IQR] p value
Diagnostic category
 Normal 64 88 [50–142] < 0.001 54 [30–89] < 0.001 110 [79–173] < 0.001
 Benign 29 84 [39–140] 66 [34–100] 141 [86–195]
 Borderline 50 59 [29–105] 84 [60–128] 131 [68–183]
 Cancer 182 50 [13–109] 106 [71–150] 144 [91–183]
 Metastatic 46 35 [12–60] 100 [70–131] 224 [162–266]
Age
 ≤ 50 85 56 [18–123] 0.032 110 [59–149] 0.808 146 [99–180] 0.755
 > 50 97 41 [7–85] 99 [74–150] 143 [83–196]
Histological subtype
 Serous 123 50 [17–101] 0.914 101 [73–145] 0.531 146 [86–197] 0.647
 Others 59 55 [7–119] 110 [64–170] 140 [107–165]
FIGO stage
 I/II 48 91 [30–122] 0.007 101 [60–143] 0.535 136 [81–163] 0.102
 III/IV 121 41 [11–76] 101 [74–150] 145 [91–199]
Tumor grade
 Well + Moderate 78 51 [12–110] 0.916 110 [80–161] 0.144 143 [83–179] 0.589
 Poor 91 50 [16–104] 98 [60–143] 140 [91–181]
CA125
 ≤ 35 24 43 [20–130] 0.238 99 [60–134] 0.632 136 [87–155] 0.290
 > 35 154 51 [11–102] 106 [73–151] 145 [91–183]
Chemosensitivity
 Sensitive 152 55 [16–113] 0.002 104 [70–150] 0.182 141 [90–182] 0.041
 Resistant 12 5.5 [0–27] 136 [89–155] 168 [147–190]
a

Calculated only 169 cases with available information of FIGO stage and tumor grade.

b

Calculated only 178 cases with available information of CA125.

c

Calculated only 163 cases with available information of chemosensitivity.

Protein expression was determined through analysis of an immunohistochemically stained tissue array, as described in the materials and methods section.