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. 2016 Oct 21;7(48):78713–78725. doi: 10.18632/oncotarget.12805

Figure 1. Knockdown of SIN3A and SIN3B.

Figure 1

Three non-overlapping shRNA constructs targeting sequences located in exon 19, 11, and 15–16 of SIN3A (sh1, sh2 and sh3 respectively) and exon 4, 20, and 3 of SIN3B (sh1, sh2, and sh3 respectively) (see Supplementary Table S1 for specific sequences) were stably transduced into MDA-MB-231 and −435. Whole cell lysates were probed by Western blot. Densitometry is shown under the blots as a ratio of SIN3A or SIN3B to β-actin normalized to the scrambled control (scr).