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. 2016 Nov 7;7(49):81698–81714. doi: 10.18632/oncotarget.13173

Figure 1. Insufficient expression of MBD3 in human glioblastoma revealed by single-molecule FCS.

Figure 1

A. Schematic for FCS technique to determine the intracellular diffusivity of fluorescent molecules. B. MBD3-GFP exhibits two distinct components of diffusivity in living SF767 cells. The component with a short diffusion time represents the free-moving proteins, while the component with a long diffusion time represents the chromatin bound proteins.