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. 2016 Oct 6;7(49):80688–80699. doi: 10.18632/oncotarget.12486

Figure 6. IQGAP1 inhibition accentuates Helicobacter pylori effect on EMT and CD44 expression in AGS cells.

Figure 6

AGS cells were cocultured with H. pylori 7.13 for 24 h. (A) Representative images of immunofluorescent staining of IQGAP1, CD44, Snail1 and Zeb1 alone (in green) or combined with F-actin (in red, phalloidin staining) and nuclei (in blue, DAPI staining). Scale bars, 10 μm. (B) Relative expression levels of the mRNA encoding IQGAP1, CD44, Zeb1, Snail1, Vimentin, E-cadherin in uninfected cells, siIQGAP1-transfected cells, infected cells and infected and siIQGAP1-transfected cells by RT-qPCR (relative to HPRT1 housekeeping gene mRNA) (n=6).