Figure 2.
Splenic pDCs show a more differentiated phenotype than do bone marrow pDCs. Spleens and bone marrow cells of uninfected mice or mice infected with LCMV were analyzed by flow cytometry. (a) Representative histograms of MHC class II, B7-1, B7-2 and CD40 expression on gated CD11c+B220+CD11b− pDCs from the bone marrow and spleen of LCMV-infected mice. (b) Mean fluorescence intensity (MFI) obtained with n = 4 mice per group (mean ± s.d.; *P ≤ 0.002).