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. 2017 Mar 7;12(3):e0172490. doi: 10.1371/journal.pone.0172490

Table 4. Clinical characteristics of inflammatory cytokines and immune cells, in which the 64 HD patients were subdivided into different AVF Qa groups before the five-years follow-up.

Variable Low AVF Qa Median AVF Qa High AVF Qa P1 value
(L vs. M)
P2 value
(L vs. H)
P3 value
(M vs. H)
Number 21 22 21
Age (year) 50.0(40.0~58.0) 56.0(50.0~70.0) 61.0(38.0~71.0) 0.12 0.25 0.65
Sex ratio (M/F) 10/11 12/10 12/9 0.95
r e 74s
0.14 0.36
AVF Qa (ml/min) 703.6±63.0 925.8±55.0 1207.9±125.0 0.0001 0.0001 0.001
KT/V 1.56±0.18 1.67±0.13 1.73±0.29 0.055 0.047 0.36
IL-2 (pg/ml) 2.57(1.78~3.55) 2.22(2.03~2.74) 3.89(2.61~5.99) 0.78 0.02 0.02
IL-6 (pg/ml) 2.19(1.79~2.60) 3.37(2.31~5.00) 4.90(3.07~7.22) 0.01 0.002 0.14
IL-10 (pg/ml) 1.55(1.02~2.47) 1.52(1.18~2.53) 1.88(1.29~3.01) 0.98 0.53 0.37
TNF-α (pg/ml) 1.45(1.19~1.56) 1.46(1.01~2.21) 1.95(1.36~2.57) 0.64 0.04 0.18
T cells 75.00(65.50~81.50) 74.50(67.00~78.25) 79.00(71.00~83.00) 0.74 0.40 0.23
Th cells 42.00(34.00~54.00) 48.00(39.5~52.00) 48.00(40.00~51.50) 0.79 0.62 0.88
Ts cells 22.00(20.00~28.50) 24.50(23.00~26.75) 27.00(24.00~35.00) 0.25 0.10 0.45
Th/Ts 1.77(1.35~2.69) 1.83(1.64~2.17) 1.52(1.29~2.08) 0.95 0.49 0.46
B cells 7.00(4.50~11.50) 10.50(7.25~14.50) 13.00(9.50~13.00) 0.50 0.08 0.45
NK cells 11.00(6.00~25.00) 11.50(5.75~22.50) 6.00(4.00~13.50) 0.84 0.18 0.45

Data are expressed as medians and quartiles for continuous variables that were not normally distributed or as the means and standard deviations for variables that are normally distributed. Comparisons between groups were performed by chi-squared tests or nonparametric tests. P<0.05 was considered statistically significant. L means low AVF Qa, M means median AVF Qa, H means high AVF Qa.