Table 4. Results of sensitivity analyses which altered cost-effective intervention.
Dataset | Scenario | The intervention that is cost-effective for each scenario at £20,000/QALY |
---|---|---|
All trials | Base case | TENS |
Shortest weekly therapist time used for acupuncture costing | Acupuncture | |
Shortest weekly therapist time used for interferential therapy costing | Interferential therapy | |
Shortened weekly therapist time—75% of benefit in first 30 mins, remainder by 1 hour | Interferential therapy | |
Shortened weekly therapist time—all benefit achieved within 20–30 minutes | Interferential therapy | |
Increase in duration of benefit of all interventions by 6 weeks | Interferential therapy | |
Increase in duration of benefit of acupuncture by 31% | Acupuncture | |
Increase in duration of benefit of interferential therapy by 45% | Interferential therapy | |
Lower 95% CrI from NMA for TENS | Acupuncture | |
Upper 95% CrI from NMA for Acupuncture | Acupuncture | |
Upper 95% CrI from NMA for Braces | Braces | |
Upper 95% CrI from NMA for NMES | NMES | |
Upper 95% CrI from NMA for Static magnets | Static magnets | |
Trials at low risk of selection bias | Base case | Acupuncture |
Shortened weekly therapist time—all benefit achieved within 20–30 minutes | Interferential therapy | |
Lower 95% CrI from NMA for Acupuncture | TENS | |
Upper 95% CrI from NMA for Insoles | Insoles | |
Upper 95% CrI from NMA for Manual therapy | Manual therapy | |
Upper 95% CrI from NMA for Static magnets | Static magnets | |
Upper 95% CrI from NMA for TENS | TENS |
NMA = network meta-analysis; NMES = neuromuscular electrical stimulation; TENS = transcutaneous electrical nerve stimulation; CrI = credible interval.