. 2017 Mar 6;6:e22152. doi: 10.7554/eLife.22152

Table 2.

Voltage-clamp protocol parameters for the five ion type classes. Times are stated in units of ms, voltages in units of mV. See Figure 3—figure supplement 1 for graphical description. Items $T_{A}^{*}$ and $T_{B}^{*}$ represent the starting and ending times, respectively, of the regions used for analysis (dashed areas in Figure 3 of the main text, as well as Figure 3—figure supplement 1).

DOI: http://dx.doi.org/10.7554/eLife.22152.019

Act	Ion type	$V_{0}$	$V_{1}$	$V_{2}$	$Δ V$	$T_{1}$	$T_{2}$	$T_{3}$	$T_{A}^{*}$	$T_{B}^{*}$
	Kv	−80	−80	70	10	100	500	100	100	700
	Nav	−80	−80	70	10	20	50	30	18	100
	Cav	−80	−80	70	10	100	500	100	98	700
	KCa	−80	−80	70	10	100	500	100	95	605
	Ih	−40	−150	0	10	100	2000	100	95	2105
Inact	Ion Type	$V_{0}$	$V_{1}$	$V_{2}$	$V_{3}$	$Δ V$	$T_{1}$	$T_{2}$	$T_{3}$	$T_{4}$	$T_{A}^{*}$	$T_{B}^{*}$
	Kv	−80	−40	70	30	10	100	1500	50	100	1600	1700
	Nav	−80	−40	70	30	10	100	1500	50	100	1580	1750
	Cav	−80	−40	70	30	10	100	1500	50	100	1580	1750
	KCa	−80	−40	70	30	10	100	1500	50	100	1595	1700
	Ih	−40	−150	−40	−120	10	100	1000	300	100	1095	1405
Deact	Ion Type	$V_{0}$	$V_{1}$	$V_{2}$	$V_{3}$	$Δ V$	$T_{1}$	$T_{2}$	$T_{3}$	$T_{4}$	$T_{A}^{*}$	$T_{B}^{*}$
	Kv	−80	70	−100	40	10	100	300	200	100	400	600
	Nav	−80	70	−100	40	10	20	10	30	20	29	80
	Cav	−80	70	−100	40	10	100	300	200	100	380	700
	KCa	−80	70	−100	40	10	100	300	200	100	395	605
	Ih	−40	−140	−110	0	10	100	1500	500	400	1595	2105
Ramp	Ion Type	$V_{0}$	$V_{1}$	$T_{1}$	$T_{2}$	$T_{3}$	$T_{4}$	$T_{5}$	$T_{6}$	$T_{7}$	$T_{8}$	$T_{9}$	$T_{A}^{*}$	$T_{B}^{*}$
	Kv	−80	70	100	800	400	400	400	200	400	100	100	100	2800
	Nav	−80	70	100	800	400	400	400	200	400	100	100	98	2800
	Cav	−80	70	100	800	400	400	400	200	400	100	100	98	2800
	KCa	−80	70	100	800	400	400	400	200	400	100	100	100	2800
	Ih	−80	70	100	800	400	400	400	200	400	100	100	100	2800
AP	Ion Type	$T_{1}$	$T_{A}^{*}$	$T_{B}^{*}$
	Kv	1800	100	1800
	Nav	1800	98	1800
	Cav	1800	98	1800
	KCa	1800	95	1655
	Ih	1800	95	1655