Table 1.
Inhibition of the animal models of lung inflammation by various plant extracts
| Plants | Extracts | Doses (mg/kg)a) | Inflammagen usedb) | Ref. |
|---|---|---|---|---|
| Acanthopanax senticosus | c) | 20 (i.v.) | LPS (i.t.) | Fei et al. (2014) |
| Aconitum tanguticum | Alkaloid fraction | 30–60 | LPS (rat) | Wu et al. (2014a) |
| Alisma orientale Juzepzuk | 80% ethanol | 300–1,200 | LPS | Han et al. (2013) |
| Angelica decursiva | 70% ethanol | 400 | LPS | Lim et al. (2014) |
| Antrodia camphorata | Methanol | 25–100 | LPS | Huang et al. (2014a) |
| Alstonia scholaris | Alkaloid fraction | 7–30 | LPS (i.t.) (rat) | Zhao et al. (2016) |
| Azadirachta indica | Water | 100/day | Cigarette smoke | Koul et al. (2012) |
| Callicarpa japonica Thunb. | Methanol | 15–30/day | Cigarette smoke | Lee et al. (2015d) |
| Canarium lyi C.D. Dai & Yakovlev | Methanol | 30/day | LPS | Hong et al. (2015b) |
| Chrysanthemum indicum | Supercritical CO2 extract | 40–120/day | LPS (i.t.) | Wu et al. (2014b) |
| Cnidium monnieri | Water | 50–200/day | Cigarette smoke extract/LPS (i.t.) | Kwak and Lim (2014) |
| Eleusine indica | 400 (i.p.) | LPS | De Melo et al. (2005) | |
| Euterpe oleracea Mart. | 50% ethanol | 300/day | Cigarette smoke | Moura et al. (2012) |
| Galla chinensis | 100/day | Cigarette smoke | Lee et al. (2015a) | |
| Ginkgo biloba | Egb761 | 0.01–1 (i.p.) | LPS (i.t.) | Huang et al. (2013) |
| Gleditsia sinensis | Water | 3.3–10/day | LPS | Choi et al. (2012) |
| Glycyrrhiza uralensis | Flavonoid fraction | 3–30 | LPS (i.t.) | Xie et al. (2009) |
| Houttuynia cordata | 70% ethanol | 400 | LPS | Lee et al. (2015b) |
| Juglans regia L. kernel | Methanol | 50–100/day | Cigarette smoke (rat) | Qamar and Sultana (2011) |
| Lonicera japonica flos | 50% ethanol | 0.4–40 | LPS (i.t.) | Kao et al. (2015) |
| Lysimachia clethroides Duby | Methanol | 20–100 (i.p.) | LPS | Shim et al. (2013) |
| Mikania glomerata Spreng and Mikania laevigata Schultz Bip. Ex Baker | 70% ethanol | 100 (s.c.) | Mineral coal dust (i.t.) (rat) | Freitas et al. (2008) |
| Morus alba | 70% ethanol | 200–400 | LPS | Lim et al. (2013) |
| Nigella sativa | Hydroethanolic extract | 80/day | Sulfur mustard (guinea-pigs) | Hossein et al. (2008) |
| Paeonia suffruticosa | Granule | 2,000 | LPS (i.t) (rat) | Fu et al. (2012) |
| Phellodendri cortex | Methanol | 100–400 | LPS (i.t.) | Mao et al. (2010) |
| Punica granatum | 0.9% NaCl | 200 (i.p.) | LPS (i.t.) | Bachoual et al. (2011) |
| Rabdosia japonica var. glaucocalyx | Flavonoid fraction | 6.4–25.6/day | LPS (i.t.) | Chu et al. (2014) |
| Schisandra chinensis Baillon | Water | 10–100 | LPS | Bae et al. (2012) |
| Schisandra chinensis Baillon | Aqueous ethanol | 1,000/day | Cigarette smoke-induced cough hypersensitivity (guinea pig) | Zhong et al. (2015) |
| Stemona tuberosa | Water | 50–200/day | Cigarette smoke | Lee et al. (2014) |
| Taraxacum officinale | Water | 2.5–10/day | LPS | Liu et al. (2010) |
| Taraxacum mongolicum hand.-Mazz | Water | 5,000–10,000 | LPS | Ma et al. (2015a) |
| Uncaria tomentosa | Water | Ozone | Cisneros et al. (2005) | |
| Viola yedoensis | Petroleum ether | 2–8 | LPS | Li et al. (2012b) |
| Formula: Dangkwisoo-san | Mixture | 100–1,000/day | LPS | Lyu et al. (2012) |
| Formula: Gingyo-san | Mixture | 1–2 | LPS (i.t.) | Yeh et al. (2007b) |
| Formula: Hochu-ekki-to (TJ-41) | Mixture | 1,000/day | LPS | Tajima et al. (2006) |
| Formula: Xia-Bai-San | Mixture | 1 | LPS (i.t.) | Yeh et al. (2006) |
| Formula: BP+LJ | Mixture | 100–400 | LPS (i.t.) (rat) | Ko et al. (2011) |
a)
All extracts were orally administered unless otherwise stated.
b)
Mice were used as experimental animals unless otherwise indicated. Administration route of inflammagens was intranasal. Intratracheal route (i.t.) was indicated. Cigarette smoke was administered by inhalation route.
c)
Due to the insufficient information provided, space remained blank.