Table IV.
Top 10 most significant results from the 4 degree of freedom Likelihood Ratio Test for SNP-SNP interactions in 1,034 Asian case-parent trios (observed test statistic, nominal p-value, and nominal permutation p-value).
| First Gene | Second Gene | Marker 1 | Marker 2 | Test Statistic |
p-value | Permutation p-value |
|---|---|---|---|---|---|---|
| ARHGAP29 | PTCH1 | rs3761910 | rs2149722 | 29.04 | 7.67E-06 | 0.03 |
| NOG | NTN1 | rs17821518 | rs12452003 | 28.79 | 8.63E-06 | 0.04 |
| MAFB | NTN1 | rs13041631 | rs72809908 | 28.16 | 1.16E-05 | 0.05 |
| BMP4 | FGFR2 | rs2738265 | rs2936861 | 27.41 | 1.64E-05 | 0.03 |
| FGFR2 | PAX7 | rs12763463 | rs11488726 | 26.23 | 2.84E-05 | 0.18 |
| 8q24 | ARHGAP29 | rs873232 | rs3789398 | 25.82 | 3.44E-05 | 0.10 |
| 8q24 | IRF6 | rs10111530 | rs6540559 | 24.94 | 5.16E-05 | 0.14 |
| NOG | PAX7 | rs227723 | rs2236832 | 24.74 | 5.67E-05 | 0.22 |
| 8q24 | NTN1 | rs10956419 | rs2429370 | 24.39 | 6.66E-05 | 0.26 |
| MSX1 | NOG | rs9291153 | rs7222986 | 24.34 | 6.81E-05 | 0.07 |