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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Bone Miner Res. 2016 Oct 28;32(3):461–472. doi: 10.1002/jbmr.3005

Fig. 2.

Fig. 2

The most significantly changed miRNAs in synovium in STA. (A) Of the 168 miRNAs that passed the QC analysis, 22 miRNAs are significantly different (ANOVA p value <0.01) by at least fourfold between D10 and nonarthritic. The dendrogram was generated using unbiased hierarchical clustering. Fold changes have been transformed so that negative values show the fold decrease. (B) Three clusters were identified following PCA of these 22 significantly different miRNAs. (C) Specific miRNAs selected by PCA that target skeletal pathways. PCA = principal component analysis.