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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Bone Miner Res. 2016 Oct 28;32(3):461–472. doi: 10.1002/jbmr.3005

Fig. 3.

Fig. 3

Expression of miRNAs in synovium and FLSs treated with pro-inflammatory cytokines. Expression of miR-486-5p, miR-708-5p, miR-186-5p, and miR-145a-5p are evaluated by qPCR analysis using whole synovial RNA samples (n =2 pools each with technical replicates, error bars are SD) (left). FLS are treated with TNF (10 ng/mL), IL-17 (50 ng/mL), IL-1 (10 ng/mL) for 3 days (right). Relative expression of miRNA was examined by qPCR (error bars are SD). NA or control (untreated) =1. miRNAs are normalized to U6. FLS =fibroblast-like synovial cell; NA =nonarthritic.