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Effects of WIN55,212-2 on 3-NP-induced lipid peroxidation in the rat striatum. Animals received WIN55,212-2 (1 mg/kg, i.p. once a day ×6 days prior to 3-NP) or vehicle, plus 3-NP (500 nmol/µl, intrastriatal bilateral dose) or vehicle. The striatal levels of lipid peroxidation are shown. Mean values ± S.E.M of n=5 rats per group are depicted; *P<0.05, different of Sham; #P<0.05, different of 3-NP group. Two-way ANOVA followed by Bonferroni’s test.
