Effect of WIN55,212-2 on the 3-NP-induced early changes in the striatal protein content of the NR1 subunit of NMDA receptor and the CB1 receptor in rat. Animals received WIN55,212-2 (1 mg/kg, i.p. once a day × 6 days prior to 3-NP) or vehicle, plus 3-NP (500 nmol/µL, intrastriatal bilateral dose). Protein content was estimated 24 h after the animals were intrastriatally lesioned. Blotting bands and their represented densities are shown. Mean values ± S.E.M of n=5 rats per group are shown; *P<0.05 and **P<0.01, different of Sham; #P<0.05, different of 3-NP group. Two-way ANOVA followed by Bonferroni’s test.