Figure 4.
Knockdown of AGR2 inhibits cell migration of AdCC cell lines. A. Western blotting showed that the protein levels of AGR2 and CD147 in SACC-LM cells were higher. The β-actin was used as loading control. B. The mRNA levels of AGR2 and CD147 were significantly increased in SACC-LM cells (Mean ± SEM, *P<0.05, **P<0.01, unpaired t test). C. Transwell migration assays revealed that knockdown of AGR2 significantly inhibited the migration ability of SACC-83 and SACC-LM cells (Mean ± SEM, **P<0.01, ***P< 0.001, unpaired t test, scale bar = 100 μm).