. 2017 Feb 15;9(2):580–590.

Table 2.

Summary of liver IRE preclinical studies including MRI acquisitions

Study	Primary aim	MRI sequences	Quantitative measures
Guo et al., 2010 [25]	To observe tumor evolution after IRE	T2-weighted TSE	Maximum lesion diameter Lesion cross-sectional area
		T1-weighted TSE
		PD-weighted TSE
Lee et al., 2010 [10]	To evaluate IRE effects on the healthy liver and their appearance at MRI	T1-weighted GRE (before contrast administration and in the hepatic arterial and portal venous phases)	None
Zhang et al., 2010 [23]	To test the possibility to detect IRE effects by MRI immediately after treatment of the healthy liver	T1-weighted GRE	Area of the ablation zone
		T2-weighted TSE
		T1-weighted TSE
		PD-weighted TSE
Guo et al., 2011 [24]	To evaluate ablation zones measures in the healthy liver by different MRI sequences	T1-weighted GRE	Area of the IRE ablation zone Area of the RE penumbra
Guo et al., 2011 [24]		IR FLASH with multiple inversion times	Area of the IRE ablation zone Area of the RE penumbra
Zhang et al., 2014 [26]	To compare alterations shown by different imaging modalities after IRE in liver tumors	T1-weighted GRE	Signal-to-noise Ratio before and after IRE
Zhang et al., 2014 [26]		T2-weighted FSE	Signal-to-noise Ratio before and after IRE

Abbreviations: TSE = Turbo Spin Echo, PD = Proton Density, GRE = Gradient Echo, IR = Inversion Recovery, FLASH = Fast Low Angle Shot, FSE = Fast Spin Echo.