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. 2017 Feb 15;9(2):591–600.

Figure 2.

Figure 2

Knockdown of miR-146a suppressed LPS-induced angiogenesis. A. HUVEC cultures were transfected with miR-146a inhibitor (LNA-anti-miR-146a) and then treated with 1 µg/ml LPS for 24 h before being subjected to qRT-PCR analysis of miR-146a expression. B. Gene ontology classification of genes that were upregulated 2.0-fold or more in GSM1224744. C. HUVEC cultures were transfected with LNA-anti-miR-146a and treated with 1 µg/ml LPS for 24 h before being subjected to the wound healing assay. Scale bar = 100 μm. D. Quantified data from C. E. Duplicate HUVEC cultures were subjected to the in vitro tube formation assay. Representative images were taken at 0 h and 24 h. Scale bar = 50 μm. F. Quantified data from E.