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. 2017 Feb 15;9(2):647–655.

Figure 5.

Figure 5

Overexpression of PTRF could rescue miR-217’s oncogene effect on cSCC. A. PTRF expression in the cSCC cell lines (Tca8113, A431, SCC13 and HSC-5) and human benign epidermal keratinocyte cell line (HaCaT) was determined by using qRT-PCR. B. The mRNA expression of PTRF was measued by qRT-PCR. C. The PTRF vetor promoted the protein expression of PTRF in the SCC13 cell. D. The proliferation of miR-217 overexpressing SCC13 cells was partially decreased after treated with PTRF vector. E. The cyclin D1 expression in the SCC13 cell was determined by qRT-PCR. F. Overexpression of PTRF suppressed cell cycle in the SCC13 cells overexpressing miR-217. G. Ectopic expression of PTRF suppressed cell invasion in the SCC13 cells overexpressing miR-217. H. The relative invasive cells were shown. *P<0.05 and **P<0.01.