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. 2017 Feb 15;9(2):700–707.

Figure 1.

Figure 1

ER stress promotes growth of lung cancer cells in 3D culture other than in 2D culture. (A) Tm/Tg treatment inhibits growth of A549 and CRL-5908 cells in 2D culture. (B) After Tm/Tg treatment, there are more spheroids compared with DMSO control group in both A549 and CRL-5908 cells in 3D culture. B Showed the representative photomicrographs of cells at × 4 original magnification. (C) Quantitative analysis of (B). **P<0.05, ***P<0.001. Data are expressed as the mean numbers of independent triplicate experiments.