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. 2017 Jan 4;117(3):1200–1214. doi: 10.1152/jn.00836.2016

Fig. 9.

Fig. 9.

Effect of a spinally administered 5-HT1A receptor antagonist on the S2 stimulation-induced modulation of the discharge in spinal dorsal horn wide dynamic range neurons in hypersensitive neuropathic animals. A: ongoing discharge rate. B: heat-evoked discharge rate. C: latency of the heat-evoked discharge. D: duration of the heat-evoked discharge. Pre = before S2 stimulation, WAY-100635 = 5-HT1A receptor antagonist (2.5 µg). Error bars represent SD (nWAY-100635 = 9, nSaline = 9), *P < 0.05, **P < 0.01, ***P < 0.005 (Bonferroni-corrected t-test).