Table 2. Characteristics of CAD patients according to the SIRT1 rs1467568 and SIRT1 rs7895833 genotypes.
| SIRT1 rs1467568 genotype | SIRT1 rs7895833 genotype | |||||
| Wild type (AA) | Variant (AG+GG) | p-value | Wild type (AA) | Variant (AG+GG) | p-value | |
| BMI (kg/m2) | 27.52 ± 0.81 | 28.57 ± 0.55 | ns | 28.02 ± 0.80 | 28.33 ± 0.59 | ns |
| Total cholesterol (mmol/l) | 5.73 ± 0.32 | 5.17 ± 0.20 | ns | 5.32 ± 0.24 | 5.46 ± 0.25 | ns |
| LDL (mmol/l) | 3.70 ± 0.29 | 3.27 ± 0.21 | ns | 3.41 ± 0.23 | 3.47 ± 0.24 | ns |
| HDL (mmol/l) | 0.98 ± 0.04 | 0.89 ± 0.03 | ns | 0.91 ± 0.04 | 0.93 ± 0.04 | ns |
| Triglycerides (mmol/l) | 2.41 ± 0.28 | 2.37 ± 0.18 | ns | 2.34 ± 0.24 | 2.38 ± 0.20 | ns |
| Fasting glucose (mmol/l) | 6.48 ± 0.50 | 6.27 ± 0.33 | ns | 6.18 ± 0.47 | 6.32 ± 0.34 | ns |
| Fasting insulin (μlU/ml) | 16.97 ± 2.21 | 15.54 ± 1.12 | ns | 14.17 ± 1.19 | 16.95 ± 1.61 | ns |
| HBA1c (%) | 6.63 ± 0.33 | 6.61 ± 0.24 | ns | 6.57 ± 0.34 | 6.60 ± 0.24 | ns |
| hsCRP (mg/l) | 9.83 ± 2.58 | 6.97 ± 0.98 | ns | 8.93 ± 2.42 | 7.78 ± 1.31 | ns |
| IL-6 (pg/ml) | 2.80 ± 0.90 | 2.45 ± 0.59 | ns | 2.41 ± 0.80 | 2.73 ± 0.68 | ns |
BMI = body mass index, LDL = low-density lipoprotein, HDL = high-density lipoprotein, HBA1c = glycated haemoglobin, hsCRP = high-sensitivity C-reactive protein, IL-6 = interleukin-6, ns = non-significant.