Table 4. Characteristics of black controls according to the SIRT1 rs1467568 and SIRT1 rs7895833 genotype.
| SIRT1 rs1467568 genotype | SIRT1 rs7895833 genotype | |||||
| Wild type (AA) | Variant (AG+GG) | p-value | Wild type (AA) | Variant (AG+GG) | p-value | |
| BMI (kg/m2) | 25.53 ± 0.54 | 27.13 ± 1.20 | ns | 25.58 ± 0.63 | 26.57 ± 0.87 | ns |
| Total cholesterol (mmol/l) | 4.12 ± 0.12 | 4.47 ± 0.23 | ns | 4.30 ± 0.13 | 4.14 ± 0.18 | ns |
| LDL (mmol/l) | 2.62 ± 0.10 | 3.02 ± 0.22 | ns | 2.78 ± 0.12 | 2.71 ± 0.16 | ns |
| HDL (mmol/l) | 1.05 ± 0.045 | 1.03 ± 0.088 | ns | 1.08 ± 0.05 | 0.99 ± 0.06 | ns |
| Triglycerides (mmol/l) | 0.99 ± 0.072 | 0.93 ± 0.15 | ns | 0.98 ± 0.08 | 0.96 ± 0.11 | ns |
| Fasting glucose (mmol/l) | 4.80 ± 0.084 | 4.90 ± 0.11 | ns | 4.87 ± 0.11 | 4.77 ± 0.08 | ns |
| Fasting insulin (μlU/ml) | 7.69 ± 0.67 | 12.11 ± 3.74 | ns | 9.21 ± 1.73 | 8.59 ± 1.10 | ns |
| HBA1c (%) | 5.83 ± 0.062 | 5.79 ± 0.082 | ns | 5.87 ± 0.07 | 5.76 ± 0.077 | ns |
| hsCRP (mg/l) | 6.64 ± 1.86 | 5.82 ± 1.23 | ns | 7.81 ± 2.42 | 4.83 ± 0.84 | ns |
BMI = body mass index, LDL = low-density lipoprotein, HDL = high-density lipoprotein, HBA1c = glycated haemoglobin, hsCRP = high-sensitivity C-reactive protein, IL-6 = interleukin-6, ns = non-significant.