Table 1.
Subject disposition (AI substudy). AI: artificial intelligence; mDOT: modified directly observed therapy; mg: milligrams.
| Parameter | Dose of ABT-126 | |||||
| Placebo | 25 mg | 50 mg | 75 mg | Overall | ||
| All subjects participating in the AI substudy, N |
|
22 | 14 | 23 | 16 | 75 |
|
|
Completed study, n (%) | 15 (68%) | 13 (93%) | 16 (70%) | 14 (88%) | 58 (77%) |
|
|
Withdrawn, n (%) | 7 (32%) | 1 (7%) | 7 (30%) | 2 (13%) | 17 (23%) |
| Subjects monitored using the AI platform, N |
|
15 | 8 | 19 | 11 | 53 |
|
|
Completed study, n (%) | 8 (53%) | 7 (88%) | 12 (63%) | 9 (82%) | 36 (68%) |
|
|
Withdrawn, n (%) | 7 (47%) | 1 (13%) | 7 (37%) | 2 (18%) | 17 (32%) |
|
|
Suspicious, n (%) | 6 (40%) | 4 (50%) | 9 (47%) | 0 (0%) | 19 (36%) |
|
|
Grandfathered, n (%) | 3 (20%) | 2 (25%) | 3 (16%) | 4 (36%) | 12 (23%) |
| Subjects monitored using mDOT, N |
|
7 | 6 | 4 | 5 | 22 |
|
|
Completed study, n (%) | 7 (100%) | 6 (100%) | 4 (100%) | 5 (100%) | 22 (100%) |
|
|
Withdrawn, n (%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |