Table I. Summarized median DHT/CONT and EST/CONT ratios for the 76 proteins that are significantly differentially expressed in primary proximal tubular cells.
| Gene names | DHT/CONT |
EST/CONT |
||||
|---|---|---|---|---|---|---|
| Median | S.E. | Significant | Median | S.E. | Significant | |
| ALDH1B1 | 7.4391 | 0.072 | YES (Upregulated) | 0.852 | 0.214 | NO |
| ALDH4A1 | 6.806 | 2.960 | YES (Upregulated) | 1.575 | 0.444 | NO |
| C14orf159 | 8.330 | 3.011 | YES (Upregulated) | 0.981 | 0.049 | NO |
| C19orf25 | 5.837 | 1.241 | YES (Upregulated) | 0.495 | NaN | NO |
| CAD | 3.704 | 3.848 | YES (Upregulated) | 1.100 | 14.303 | NO |
| CALR | 7.818 | 1.205 | YES (Upregulated) | 0.981 | 0.576 | NO |
| CASP6 | 5.212 | 1.577 | YES (Upregulated) | 1.232 | 0.428 | NO |
| CDC2;CDK1 | 20.344 | 10.175 | YES (Upregulated) | 1.386 | 1.118 | NO |
| CDK4 | 1.664 | 0.095 | NO | 4.016 | 2.809 | YES (Upregulated) |
| CDK5RAP3 | 8.448 | 0.470 | YES (Upregulated) | 0.947 | 0.021 | NO |
| CDKN2AIP | 6.325 | 0.988 | YES (Upregulated) | NaN | NaN | NO |
| CTSC | 8.085 | 2.518 | YES (Upregulated) | 0.943 | 0.410 | NO |
| CTSZ | 8.807 | 0.076 | YES (Upregulated) | 0.952 | 0.080 | NO |
| DDAH2 | 1.171 | 1.905 | NO | 7.923 | 2.302 | YES (Upregulated) |
| DSG2 | 3.466 | 1.034 | YES (Upregulated) | 2.618 | 0.891 | YES (Upregulated) |
| DUSP23 | 1.232 | 0.625 | NO | 2.664 | 0.351 | YES (Upregulated) |
| ECHS1 | 6.356 | 0.933 | YES (Upregulated) | 0.973 | 0.079 | NO |
| EDIL3 | 1.488 | 1.519 | NO | 2.216 | 0.611 | YES (Upregulated) |
| F11R | 1.955 | 0.596 | NO | 1.914 | 0.279 | YES (Upregulated) |
| FAM98B | 2.897 | 0.806 | NO | 10.421 | 8.163 | YES (Upregulated) |
| GATAD2B | 1.928 | 0.342 | NO | 2.380 | 0.192 | YES (Upregulated) |
| GGH | 6.630 | 0.150 | YES (Upregulated) | 0.875 | 0.182 | NO |
| GLDC | 1.483 | 0.505 | NO | 2.482 | 0.567 | YES (Upregulated) |
| GLS | 6.892 | 1.572 | YES (Upregulated) | 0.854 | 0.362 | NO |
| GLUD1;GLUD2 | 9.265 | 1.726 | YES (Upregulated) | 0.957 | 0.351 | NO |
| GNA13 | 17.180 | 4.978 | YES (Upregulated) | 9.777 | 9.754 | NO |
| GNPNAT1 | 5.626 | 1.631 | YES (Upregulated) | 2.171 | 0.001 | YES (Upregulated) |
| GPI | 12.068 | 9.117 | YES (Upregulated) | 1.242 | 3.165 | NO |
| HADHA | 8.027 | 1.105 | YES (Upregulated) | 0.882 | 0.683 | NO |
| HADHB | 7.514 | 1.955 | YES (Upregulated) | 0.990 | 0.981 | NO |
| HEXB | 7.279 | 2.790 | YES (Upregulated) | 0.475 | 0.225 | NO |
| HPCAL1;HPCA;NCALD | 6.180 | 0.548 | YES (Upregulated) | 0.848 | 0.831 | NO |
| HSPA14 | 2.183 | 2.053 | YES (Upregulated) | 2.030 | 0.477 | NO |
| HYOU1 | 11.009 | 0.051 | YES (Upregulated) | 0.790 | 0.057 | NO |
| KHSRP | 13.118 | 3.911 | YES (Upregulated) | 0.794 | 1.575 | NO |
| LETM1 | 6.306 | 0.888 | YES (Upregulated) | 0.974 | 0.618 | NO |
| LTN1 | 0.789 | 0.147 | NO | 2.683 | 0.257 | YES (Upregulated) |
| MAN2B1 | 4.416 | 2.410 | YES (Upregulated) | 1.669 | 0.359 | NO |
| MCM4 | 8.936 | 13.031 | YES (Upregulated) | 0.203 | 0.610 | NO |
| MDH2 | 9.249 | 2.752 | YES (Upregulated) | 0.792 | 0.351 | NO |
| MRPL40 | 2.273 | 0.496 | YES (Upregulated) | 3.368 | NaN | NO |
| MSH6 | 1.443 | 0.338 | NO | 2.255 | 3.419 | YES (Upregulated) |
| MYEF2 | 6.874 | 0.127 | YES (Upregulated) | 0.705 | NaN | NO |
| MYO5B | 2.852 | 0.321 | NO | 3.176 | 0.705 | YES (Upregulated) |
| NASP | 3.023 | 1.839 | YES (Upregulated) | 0.922 | 0.729 | NO |
| NUDT15 | 0.881 | NaN | NO | 2.576 | 0.008 | YES (Upregulated) |
| NUP188 | 2.734 | 1.835 | YES (Upregulated) | 0.767 | 0.062 | NO |
| PALLD | 5.965 | 3.219 | YES (Upregulated) | 2.502 | 5.275 | NO |
| PARK7 | 11.700 | 5.605 | YES (Upregulated) | 1.168 | 0.158 | NO |
| PCBD1 | 6.425 | 3.355 | YES (Upregulated) | 1.104 | 0.199 | NO |
| PDHB | 8.464 | 2.035 | YES (Upregulated) | 0.782 | 1.070 | NO |
| PLBD2 | 7.145 | 4.383 | YES (Upregulated) | 1.271 | 1.318 | NO |
| PPIL3 | 3.224 | 2.113 | YES (Upregulated) | 1.783 | 1.372 | NO |
| PPM1G | 15.859 | 1.541 | YES (Upregulated) | 3.151 | 1.825 | NO |
| PSAP | 9.220 | 3.803 | YES (Upregulated) | 1.091 | 0.865 | NO |
| PTBP1 | 10.770 | 4.759 | YES (Upregulated) | 0.947 | 2.358 | NO |
| QPRT | 3.164 | 2.123 | YES (Upregulated) | 1.187 | 0.490 | NO |
| RABGGTA | 2.152 | 1.583 | YES (Upregulated) | 1.495 | 0.121 | NO |
| RIPK1 | 6.101 | 4.253 | YES (Upregulated) | 1.347 | 0.465 | NO |
| SDF4 | 8.346 | 0.535 | YES (Upregulated) | 0.996 | 0.556 | NO |
| SFN | 2.435 | 0.263 | NO | 2.558 | 0.180 | YES (Upregulated) |
| SLC4A1AP | 2.952 | 0.878 | YES (Upregulated) | 1.078 | 0.047 | NO |
| SOD2 | 6.109 | 1.587 | YES (Upregulated) | 1.145 | 1.153 | NO |
| SRSF2;SRSF8 | 6.395 | 3.138 | YES (Upregulated) | 1.507 | 6.084 | NO |
| SUCLG2 | 7.160 | 0.323 | YES (Upregulated) | 0.926 | 0.626 | NO |
| TALDO1 | 7.875 | 3.891 | YES (Upregulated) | 1.025 | 0.292 | NO |
| TKT | 3.950 | 2.514 | YES (Upregulated) | 1.156 | 0.338 | NO |
| TMSB15B;TMSB15A | 0.585 | 2.257 | NO | 5.868 | 2.490 | YES (Upregulated) |
| TMSB4X | 15.253 | 9.388 | YES (Upregulated) | 1.263 | 0.124 | NO |
| TNRC11;MED12 | 7.550 | 1.477 | YES (Upregulated) | NaN | NaN | NO |
| TOP2A | 5.088 | 2.515 | YES (Upregulated) | 3.521 | 2.395 | NO |
| TUBB6 | 3.253 | 3.862 | YES (Upregulated) | 0.959 | 0.179 | NO |
| UACA | 2.560 | 5.024 | NO | 2.852 | 0.217 | YES (Upregulated) |
| UHRF1 | 1.279 | 0.522 | NO | 0.187 | 0.029 | YES (Downregulated) |
| VPS4A | 4.048 | 0.848 | YES (Upregulated) | 1.041 | 0.125 | NO |
| WDR5 | 2.186 | 2.707 | YES (Upregulated) | 1.485 | 0.757 | NO |