Table 2. Clinical characteristics and biopsy outcomes of the study population stratified by biopsy outcome detail.
| Variables | Non-Cancer | Low grade Cancer (Gleason score = 6 or 7) | High grade Cancer (Gleason score >=8) | P-value |
|---|---|---|---|---|
| No.Patients | 763 | 152 | 103 | — |
| Age, years | 65 (59, 70) | 68 (62, 74) | 68 (63, 75) | <0.001* |
| PSA, ng/ml | 8 (6, 11) | 10 (7, 13) | 11 (8, 14) | <0.001* |
| %fPSA | 14.9 (9.7, 20.9) | 12.3 (8.7, 16.5) | 10.8 (8.1, 15.1) | <0.001* |
| Prostate volume, cm3 | 45 (31, 60) | 36 (29, 45) | 33 (23, 42) | <0.001* |
| DRE Abnormal (%) | 8 | 11 | 25 | 0.009** |
| TRUS or MRI Abnormal (%) | 22 | 33 | 41 | 0.021** |
| Height, cm | 170 (166, 173) | 170 (165, 174) | 170 (165, 173) | 0.776* |
| Weight, kg | 68 (62, 75) | 68 (61, 75) | 68 (60, 75) | 0.618* |
| Recent BMI, kg/m2 | 24 (22, 25) | 24 (22, 25) | 24 (21, 25) | 0.924* |
| Waist circumference, cm | 85 (81, 90) | 85 (80, 91) | 87 (81, 91) | 0.394* |
| Hip circumference, cm | 95 (91, 99) | 95 (90, 100) | 95 (90, 99) | 0.573* |
| WHR | 0.900 (0.876, 0.927) | 0.902 (0.882, 0.924) | 0.918 (0.891, 0.938) | <0.001* |
| Smokers (%) | 0.214** | |||
| ever | 41 | 44 | 50 | |
| never | 59 | 56 | 50 | |
| Alcohol use (%) | 0.712** | |||
| ever | 39 | 41 | 36 | |
| never | 61 | 59 | 64 | |
| Hypertension (%) | 33 | 35 | 38 | 0.651** |
| Diabetes mellitus (%) | 10 | 10 | 9 | 0.924** |
| Biopsy outcome = cancer, n | 0 | 152 | 103 | — |
| Gleason score, n (%) | — | |||
| 6 | — | 55 (36) | — | |
| 7 | — | 97 (64) | — | |
| 8 | — | — | 43 (42) | |
| 9 | — | — | 49 (48) | |
| 10 | — | — | 11 (10) |
^Continuous variables are shown as the median value and interquartile range.
*Using the Kruskal-Wallis test.
**Using the chi-squared test.